期刊文献+

精神分裂症患者胰岛素分泌异常的影响因素分析 被引量:4

下载PDF
导出
摘要 2005年5月至2007年5月,我们观察了67例住院精神分裂症患者,发现其中36例空腹胰岛素水平低于正常,而餐后2h胰岛素水平达到或超过空腹胰岛素水平的5~10倍。为探究原因,我们将其与未曾诊断合并糖尿病的非精神分裂症患者74例做对照,并对两组患者各项指标进行了统计分析,报告如下。
出处 《北京医学》 CAS 2008年第6期371-372,共2页 Beijing Medical Journal
  • 相关文献

参考文献7

二级参考文献17

  • 1[1]Dwyer DS,Bradley RJ,Kablinger AS,et a1.Glucose metabolism in relation to schizophrenia and antipsychotic drugtreatment¨].Ann Clin Psychiatry,2001,13:103.
  • 2[3]Wozniak KM,Linnolia M.Hyperglycemic properhes of serotonin receptor antagomsts[J].Life Sci,1991,49:101.
  • 3[5]Yazici KM,Erbas T,Yaziei AH.The effect of clozapine on glucose metabolism[J].Exp Clin Endocrinol Diabetes,1998,106:475.
  • 4Ardizzone TD, Bradley RJ, Freeman Am, et al. Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine[ J ]. Brain Res, 2001,923:82-90.
  • 5Lindenmayer JP, Czobor P, Volavka J, et al. Changes in glucose and cholesterol levels in patients with schizophrenia treated with typical or atypical antipsychitics[ J]. Am J Psychiatry, 2003,160: 290-296.
  • 6Dixon L, Weiden P, Delahanty J, et al. Prevalence and correlates of diabetes in national schizophrenia samples [ J ]. Schizophr Bull, 2000, 26:903-912.
  • 7Dwyer DS, Donohoe D. Induction of hyperglycemia in mice with atypical antipsychotic drugs that inhibit glucose uptake[J]. Pharmacol Biochem Behav, 2003,75: 255-260.
  • 8Henderdon DC, Cagliero E, Gray C, et al. Clozapine, diabetes mellitus,weight gain, and lipid abnormalities: a five-year naturalistic study[ J].Am J Psychiatry,2000, 157: 975-981.
  • 9Sowell MO, Mukhopadhyay N, Cavazzoni P,et al. Hyperglycemic clamp assessment of insulin secretory responses in normal subjects treated with olanzapine, risperidone, or placebo[J]. J Clin Endocrinol Metab, 2002,87: 2918-2923.
  • 10Atmaca M, Kuloglu M, Tezcan E, et al. Serum leptin and triglyceride levels in patients on treatment with atypical antipsychotics[ J ]. J Clin Psychiatry, 2003,64: 598-604.

共引文献129

同被引文献35

  • 1Evoy JP, Meyer JM, Goff DC,et al. Prevalence of the metabolic syn- drome in patients with schizophrenia: Baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES Ⅲ [ J ]. Schizophr Res,2005,29 ( 1 ) :19 - 32.
  • 2Maguire GA. Prolactin elevation with antipsychotie medications: mechanisms of action and clinical consequences [ J ]. J Clin Psychi- atry ,2002,63 ( Suppl 4) :56 - 62.
  • 3F M Reis, A M Reis, C C Coimbra. Effects of hyperprolactinaemia on glucose tolerance and insulin release in male and female rats [ J ]. Journal of Endocrinology, 1997,153 ( 3 ) :423 - 428.
  • 4Foss MC, Paula FJ, Paccola GM, et al. Peripheral glucose metabo- lism in human hyperprolactinemia [ J ]. Clin Endocrinol ( Oxf), 1995,43(6) :721 -726.
  • 5Serri, Beauregard H, Rasio E, et al. Decreased sensitivity to insu- lin in women with microprolactinomas [ J ]. Fertil Steril, 1986,45 (4) :572 -574.
  • 6Serri O, Ling L, Mamputu JC, et al. The influences of hyperpro- lactinemia and obesityon cardiovascular risk markers: effects of cabergoline therapy [ J ]. Clin Endocrinol ( Oxf), 1986,64 (4) : 366 - 370.
  • 7Tuzcu A, Bahceci M, Dursun M, et al. Insulin sensitivity and hyper- prolactinemia [ J ]. J Endocrinol Invest,2003,26 (4) : 341 - 346.
  • 8Asai - Sato M, Okamoto M, Endo M, et al. Hypoadiponectinemmia in lean lactating women: prolactin hlhibits adiponectinsecretion from human adipocytes [ J ]. Endocr J,2006,53 (4) :555 - 562.
  • 9Nilsson L, Binart N, Bohlooly - Y M, et al. Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue[ J]. Biochem Biophys Res Commun ,2005,331 (4) : 1120 - 1126.
  • 10Rathgeb IB, Winkler B, Steele R, et al. Effect of ovine prolactin ad- ministration on glucose metabolism and plasma insulin levels in the dog [ J ]. Endocrinology, 1971,88 ( 3 ) : 718 - 722.

引证文献4

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部