血清前白蛋白和C-反应蛋白联合检测临床意义

The Clinical Significance of Joint Detection of Serum Prealbumin and C-reactive Protein

目的:通过对血清前白蛋白检测,评价血清前白蛋白在临床多范围应用方面的重要性,以及和C-反应蛋白联合检测的临床价值。方法:血清前白蛋白采用免疫透射比浊法,C-反应蛋白采用散射免疫比浊法。结果:患者血清前白蛋白检测结果为(105.0±86.4)mg/L,较正常对照组偏低,和对照组比较具有显著性的差异(P<0.01)。患者C-反应蛋白检测结果为(41.2±36.8)mg/L,较正常对照组偏高,和对照组比较具有显著性的差异(P<0.01)。结论:血清前白蛋白含量在肝病、肾病、脑外伤、急性炎症感染等患者中明显降低,C-反应蛋白的含量明显升高,两者联合检测在指导临床评估患者病情严重程度方面是一个敏感指标。

Objective：Through detecting serum prealbumin to evaluate the importance of prealbumin in many fields of clinical application and the clinical value of the joint detection with C-reactive protein. Method： Serum prealbumin was measured by immunoturbidimetic assay, and C-reactive protein was measured by immune scatter turbidimetry. Results： Serum prealbumin level in patients was（105.0± 86.4）mg/L which was lower than that of the control group, and the difference between the two groups was obvious （P〈0. 01）. C-reactive protein level in patients was（41.2±36.8）mg/L which was higher than that of the control group, and there was significant difference between the two groups （P〈 0.01）. Conclusion：The content of serum prealbumin is decreased in patients with liver disease,nephropathy, head injury and acute iniury and acute inflammation, while C-reactive protein level is increased. The joint detection is a sensitive index in the evaluation of severity of patients.