胆汁动态研究动物模型的建立与应用研究

EXPERIMENTAL ANIMAL MODEL FOR CONSECUTIVE STUDY OF BILE AND GALLSTONE FORMATION IN RABBIT

应用“导管胆肠皮下转流法”建立家兔胆色素结石胆汁的动态研究动物模型，并应用该模型检测胆汁中免疫复合物含量的变化。结果显示：在胆色素结石形成过程中，胆汁中免疫复合物含量呈从低到高的变化规律。

Choledochojejunal shunt was performed in rabbits by inserting tubes of different calibre into the hep-atic duct and proximal jejunum separately with ligation of common bile duct and connecting two tubes under the skin ofabdominal wall for subsequent collections of bile to detect the immune complex. The consecutive observation demon-stated a regularity of immune complex in bile increasing from the lower to the higher level in the process of formationof pigmental stone.