受体阻断治疗女性膀胱过度活动症的疗效观察

Pharmacological Treatment for Female Urethral Syndrome Via a Multi-receptor Intervention

目的探讨采用受体阻断治疗女性膀胱过度活动症的效果。方法不使用抗菌药物,分别选用M胆碱受体阻滞剂、α-受体阻滞剂、钙离子阻滞剂及盐酸黄酮哌酯,或加用三环类抗抑郁药阿米替林治疗113例女性膀胱过度活动症患者,观察治疗的效果。结果113例患者中治愈78例(69%),好转27例(24%),无效8例(7%)。结论针对女性膀胱过度活动症患者采用受体阻断治疗效果较好。

Objective To investigate the value of treating Female Urethral Syndrome via a multireceptor intervention.Methods Without any antibiotics,113 female patients suffering from urethral syndrome were treated by combination therapy with different pharmacological agents,including anticholinergic agent,alpha-adrenergic antagonists,calcium antagonistic,amitriptyline,and flavoxate.Results The medication therapy resulted in a cure rate of 69%,and a symptom improve rate of 24%.Conclusion The combination therapy via multi-receptor intervention is effective for female urethral syndrome.