不同类型血液制剂输血不良反应的调查

Investigation of Transfusion Reaction for Different Blood Products

目的了解不同血液制剂输血不良反应的发生情况。方法对2003年1月—2007年6月临床用血的输血相关数据进行统计分析。结果输注含白细胞血液制剂的不良反应中悬浮红细胞为1.87%、全血为5.62%、冰冻血浆为0.97%;输注去白细胞血液制剂不良反应中,去白细胞悬浮红细胞为0.16%,去白细胞全血为0.16%,去白细胞冰冻血浆为0.20%。含白细胞类血液制剂输血不良反应率为2.19%,去白细胞类血液制剂输血不良反应率为0.16%,两者比较差异有统计学意义(P<0.01)。结论去白细胞类血液制剂可以有效降低输血不良反应率。

Objective To investigate the condition of untoward reaction of transfusion for different blood products.Methods Statistical analysis was performed about the data of untoward reaction of transfusion for different blood products from January 2004 to June 2007.Results The untoward reaction rates of transfusion in leukocyte-included blood products were 1.87% for red cell suspension,5.62% for whole blood and 0.97% for frozen plasma,And untoward reaction rates of transfusion in eukocyte-filtrated blood products were 0.16% for red cell suspension,0.16 % for whole blood and 0.20% for frozen plasma,The untoward reaction rates of transfusion for leukocyte-included blood products and leukocyte-filtrated blood products were 2.19 % and 0.16% respectively,with a significant difference （P〈0.01）.Conclusion The leukocyte-filtrated blood products could effectively reduce the untoward reaction rate of transfusions.