摘要
趋化因子是能使细胞发生趋化作用的细胞因子的总称，为一类结构、功能相似，相对分子质量为8000-10000的小分子蛋白质，由中性粒细胞、单核细胞等多种细胞分泌产生。趋化因子与其受体相互作用，在多种急、慢性肺部炎性疾病及肺肿瘤中起重要作用。本文仅对趋化因子的分类、结构、功能及其在肺部疾病中的作用进行综述。
Chemokines belong to a family of cytokines with chemotactic activity for cells,which are micromolecule proteins of 8000-10 000 with similar structure and function, secreted by leukocyte, monocyte and so on. Chemokines interact with receptors, which play an important role in kinds of acute/chronic inflammatory disease of lung. The paper overviews the categorization, structure, function of chemokines and its effect on pulmonary disease.
出处
《国际呼吸杂志》
2008年第11期696-700,共5页
International Journal of Respiration
