我院实施《抗菌药物临床应用指导原则》前、后住院患儿抗菌药物应用对比分析

Use of Antibacterials in Pediatric Inpatients Before and After the Introduction of Guidelines for Clinical Use of Antibacterials

目的：评价《抗菌药物临床应用指导原则》的实施情况。方法：随机抽取我院2003年6～12月（干预前）与2005年6～12月（干预后）儿科出院病历各200份，按预先设计好的“抗菌药物应用对比调查表”填写，对数据进行统计、分析。结果：干预后我院儿科抗菌药物应用率减少17．50％、联合用药率减少32．10％，合理用药率增加22．05％、药敏试验率增加11．84％，药物利用指数均≤1。结论：我院住院患儿抗菌药物应用渐趋合理，但仍需进一步提高合理用药水平。

OBJECTIVE： To evaluate the practice of the Guidelines for Clinical Use of Antibacterials in our hospital. METHODS： 200 medical records of pediatric inpatients who had been discharged from our hospital were randomly sampled between June to December in 2003 （before intervention） and between June to December in 2005 （after intervention） for a statistical analysis in respect of the use of antibacterials in which the pre - designed questionaire on the contrast analysis of clinical application of Antibacterials were filled. RESULTS： After the introduction of the guidelines, the rate of using antibacterials decreased by 17.50%, the rate of combined use of antibacterials decreased by 32.10%, the rate of rational use increased by 22.05%, the rate of susceptibility test increased by 11.84%. The Drug Utilization Index for all the antibacterials was no more than 1 （≤1）. CONCLUSION： The use of antibacterials in pediatric inpatients in our hospital tends to be rational, but the rational administration of antibacterials remains to be further improved.