ICU患者感染病原菌及耐药性分析

Pathogens and drug resistance in intensive care unit patients

目的对ICU重症监护病房主要感染病原菌及其耐药性进行分析,为临床合理用药提供依据。方法ICU患者病原菌用VITEK32生物梅里埃鉴定仪鉴定,采用K-B法进行药敏试验,并对病原菌种类及其耐药性运用WHONET5.4软件进行分析总结。结果共检出病原菌298株,其中革兰阴性杆菌182株,占61%;革兰阳性球菌116株,占39%。占病原菌前五位的分别是Aba56株,占总病原菌的19%;Pae54株,占18%;Scn45株,占15%;Sau44株,占15%;Kpn16株,占5%。结论ICU患者感染病原菌以革兰阴性杆菌为主,鲍曼不动杆菌为主要感染病原菌。

Objective To investigate the distribution and the drug resistance of main bacteria from ICU patients , and to provide the reference for clinical prevention and treatment. Methods The pathogens from ICU patients were identified by Vitek- 32 of Bio- Merieux, the antibiotic susceptibility was detected by K- B method , and the data were analyzed using WHONEIS. 4 software. Results 298 strains in total were isolated,of which 182 were Gram- negative （accounting for 61%） and 116 were Gram- positive （accounting for 39%）. The first five predominant pathogens were Aba 56 strains （ 19% ）, Pae 54 strains（ 18% ）, Scn 45 strains（ 15% ）, San 44strains（ 15% ）, and Kpn 16 strains （5%）. Conclusions The main pathogens in ICU patients are Gram- negative bacteria, and Acinetobacter baumannii is the major pathogen.