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短期应用阿托伐他汀对不稳定型心绞痛病人超敏C反应蛋白的影响 被引量：1

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摘要 目的观察短期应用阿托伐他汀对于不稳定型心绞痛病人超敏C反应蛋白(hs-CRP)的影响。方法116例不稳定型心绞痛病人随机分为两组。对照组应用常规药物治疗(包括硝酸酯类药物、抑制血小板聚集药物、β-受体阻滞剂、血管紧张素转换酶抑制剂、钙拮抗剂等),治疗2周;治疗组在常规治疗的基础上加阿托伐他汀20mg;每日1次口服,治疗2周。治疗前后测定三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)及hs-CRP的水平。结果治疗组经过2周的治疗后TG及HDL-C变化不明显(P>0.05);LDL-C、TC及hs-CRP显著下降(P<0.01)。对照组经过2周治疗血脂各指标及hs-CRP前后无明显改变。治疗组治疗前后hs-CRP的变化与血脂的变化无显著相关性(P>0.05)。结论短期应用阿托伐他汀治疗对LDL-C、TC及hs-CRP有显著降低作用。阿托伐他汀对于hs-CRP的降低作用与其对于血脂的降低作用不完全相关。
作者 乔梁
机构地区 辽宁省锦州市中心医院
出处 《中西医结合心脑血管病杂志》 2008年第6期712-714,共3页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词 不稳定型心绞痛 阿托伐他汀 超敏C反应蛋白
分类号 R541.4 [医药卫生—心血管疾病] R256.2 [医药卫生—中医内科学]
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参考文献10

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中西医结合心脑血管病杂志
2008年 第6期

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