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多西他赛联合顺铂、氟尿嘧啶治疗进展期胃癌近期疗效观察 被引量:4

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摘要 目的 观察多西他赛联合顺铂、氟尿嘧啶方案治疗晚期胃癌的近期疗效和毒副反应。方法 对31例进展期胃癌患者采用多西他赛75/m^2 d1静滴1小时,用药前均予预处理;顺铂20mg/m^2静滴d1~d5,氟尿嘧啶750mg/m^2持续静滴120小时,每4周重复,至少治疗2周期,按WHO标准进行评价。结果 31例均可评价疗效,其中完全缓解2例,部分缓解14例,总有效率为51.6%;剂量限制性毒性主要表现为骨髓抑制。结论 多西他赛联合顺铂、氟尿嘧啶方案治疗进展期胃癌患者疗效确切,毒副反应可以耐受。
出处 《实用肿瘤杂志》 CAS 2008年第3期264-265,共2页 Journal of Practical Oncology
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