摘要
多发性硬化(multiple sclerosis,MS)长期以来一直被认为是中枢神经系统白质区域炎症性脱髓鞘病变。虽然早有研究显示MS患者大脑皮质和脑干的核团有脱髓鞘斑块出现,但是由于这种病变在常规的髓鞘染色及影像学检查中很难被发现,所以既往MS的灰质病变很少受到重视。近年来,随着对病灶更加敏感的免疫组织化学技术和神经影像学技术的应用,MS的灰质病变越来越受到研究者们关注。
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2008年第6期423-425,共3页
Chinese Journal of Neurology
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共引文献15
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引证文献1
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1段云云,李坤成,刘亚欧,梁佩鹏,贾秀琴,于春水,秦文,叶静,孙慧.应用体素的形态学研究复发缓解型多发性硬化患者的全脑灰质萎缩特点[J].中华神经科杂志,2011,44(7):460-463. 被引量:5
二级引证文献5
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1段云云,李坤成,刘亚欧,任卓琼,黄靖,叶静,董会卿,陈海.复发-缓解型多发性硬化患者丘脑扩散张量成像研究[J].中国现代神经疾病杂志,2012,12(2):143-146. 被引量:4
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2段云云,刘亚欧,梁佩鹏,黄靖,任卓琼,叶静,董会卿,陈海,李坤成.应用基于体素的形态测量学方法分析视神经脊髓炎患者的脑体积变化[J].中华放射学杂志,2012,46(11):983-987. 被引量:4
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3陈琪,周福庆,王博,王杏,曾献军,况红妹,占洁,龚洪翰.复发缓解型多发性硬化脑MR形态改变——基于体素的形态测量研究[J].实用放射学杂志,2013,29(9):1381-1385. 被引量:6
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4周福庆,龚洪,庄莹,张宁,陈琪,张悦,何来昌.复发缓解型多发性硬化患者丘脑结构和内源性功能活动幅度的磁共振研究[J].实用放射学杂志,2014,30(3):369-373. 被引量:4
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5余晖,刘艳,蒲伟,黄明明,沈桂权,李小宝,廖欣,冯辉,徐竹,官志忠.联合应用VBA和TBSS方法检测复发缓解型多发性硬化患者脑损害[J].临床放射学杂志,2015,34(9):1384-1388. 被引量:3
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