门诊处方抗菌药物应用分析

Antibacterial Drug Use Analyzed from Outpatients′ Prescriptions

目的了解医院门诊处方抗菌药物的应用现状,促进临床合理应用抗菌药物。方法随机抽取医院2007年7月连续5个周一的门、急诊处方进行调查分析。结果处方总计5038张,使用抗菌药物的处方1585张,占处方总量的31.64%,其中,头孢类药物使用率最高,其次为喹诺酮类;一联用药1053张,二联用药401张,三联105张,>四联26张。结论头孢菌素类、喹诺酮类抗菌药物使用比例较大,存在剂量偏大,给药途径、用法不尽合理等问题。

OBJECTIVE To investigate the current situation and rationality of clinical usage of antibacterial drugs from clinic prescriptions and to promote rational usage of drugs in our hospital. METHODS According to the same method and criterion, 5038 prescriptions were investigated retrospectively by utilizing the designed questionnaire. RESULTS The total application rate of antibacterial drugs was 31.46 %, the application rate of cephalosporins was the highest, and that of quinolones was the next. For the combined usage of antibacterial drugs, 1053 prescriptions were with one drug, 401 prescriptions were with two, 105 were with three, and 26 were with more than four drugs. CONCLUSIONS The consumption of antimicrobials is so high especially in their doses and irrational usage.