老年慢性细菌性前列腺炎病原菌及耐药性检测

Pathogenic Bacteria Causing Chronic Bacterial Prostatitis:An Investigation into Their Spread Status and Drug-resistance

目的探讨老年慢性细菌性前列腺炎的病原菌分布与耐药性,为临床提供疾病诊断及治疗依据。方法采集老年慢性前列腺炎患者的前列腺液进行细菌培养和体外药敏试验,并进行统计分析。结果216例老年慢性前列腺炎患者的前列腺液中共检出病原菌140株,其中革兰阳性菌84株,占60.0%,以金黄色葡萄球菌为主;革兰阴性菌56株,占40.0%,以大肠埃希菌为主;前列腺炎病原菌对常用抗菌药物已产生了耐药性,检出耐甲氧西林葡萄球菌(MRS)24株,占葡萄球菌属总数的34.8%;产ESBLs病原菌占肠杆菌科细菌总数的35.6%。结论老年慢性细菌性前列腺炎具有难治性和迁延性,应加强病原菌耐药性检测,提高治愈率。

OBJECTIVE To investigate the spread status and drug-resistance of pathogenic bacteria causing chronic bacterial prostatitis among the senile patients, and provide the reference for clincal diagnosis and treatment. METHODS Prostatic fluid from the senile patients with chronic bacterial prostatitis was collected, and bacterial cultures and susceptibility tests were performed. The data were analyzed statistically. RESULTS Among 216 prostatic fluid specimens from the senile patients with chronic bacterial prostatitis, 140 isolates of pathogenic bacteria were detected. In these strains, Gram-positive cocci accounted for 60.0% and most of them were Staphy- lococcus aureus. Gram-negative bacilli accounted for 40.0% and most of them were Escherichia coll. Pathogens causing prostatitis have been resistant to the common antibiotics, Among the total staphylococci, meticillin- resistant Staphylococcus （MRS） accounted for 34. 8%. And among the total Enterobacteriaceae, ESBLs producing bacteria accounted for 35. 6%. CONCLUSIONS Chronic bacterial prostatitis in the senile patients possesses intractability and persisting. It is important to monitor the pathogens and their drug-resistance.