摘要
目的探讨急性缺血性脑卒中的静脉溶栓治疗及护理措施。方法对39例发病在6h以内的急性缺血性脑卒中患者(A组),男27例,女12例,年龄50～75岁,静脉注射重组组织型纤溶酶原激活剂(rt-PA)8mg,随后60min内持续静脉泵入rt-PA42mg。溶栓后12h开始皮下注射依诺肝素,连续应用7d。溶栓前中后给予相应的护理监测和措施。非溶栓组(B组)39例,不用溶栓剂及依诺肝素(使用川芎嗪160mg静脉滴注,连续应用7d,其余治疗同溶栓组)。结果rt-PA溶栓治疗后39例溶栓患者的神经功能缺损和患肢肌力均获得不同程度的改善,总显效率达79.4%,无护理并发症发生。结论对发病6h以内的急性缺血性脑卒中患者应用rt-PA溶栓治疗,可降低患者神经功能缺损,最大限度地恢复脑的正常功能,效果满意安全。
Objective To investigate the effects of intravenous thrombolytic treatment of acute ischemic stroke with recombinant tissue-type plasminogen activator （rt-PA） and necessary nursing care measures. Methods 39 patients of acute ischemic stroke with the onset within 6 h, 27 males and 12 females, aged 50-75, received intravenous injection of rt-PA 8 mg, and then continuous intravenous infusion of rt-PA 42 mg. 12 h after the thrombosis enoxaparin was injected subcutaneously for 7 d. Nursing care measures and monitoring were carried out before, during, and after the thrombolytic procedures. Another 39 patients of acute ischemic stroke with the onset within 6 h received the routine treatment （Intravenous infusion of ligustrazine 160 mg for 7 d. ）without rt-PA and enoxaparin. Resu Its The clinical manifestations of neurological deficit and decreased muscle strength recovered to different extents. The recanalization rate of thrombosed vessels was 79.4%. No nursing complications occurred. Cone I us i on Efficient and safe for acute ischemic stroke within 6 h after the onset, rt-PA thrombolysis can restore the defective nerve functions.
出处
《中国急救复苏与灾害医学杂志》
2008年第6期359-361,共3页
China Journal of Emergency Resuscitation and Disaster Medicine
基金
北京市科学技术委员会科研基金资助项目(2001541)
