糖尿病合并冠心病患者血清尿酸水平分析

THE ANALYSIS ON SERUM URIC ACID LEVEL OF PATIENTS WITH CORONARY HEART DISEASE AND DIABETES

目的探讨糖尿病合并冠心病患者尿酸水平与冠状动脉病变的关系。方法2型糖尿病患者108例,经冠状动脉造影检查确诊为冠心病患者52例,为冠心病组;56例确诊为未合并冠心病患者,为非冠心病组;根据冠状动脉受累情况,分为1支、2支、3支病变组,并测定血尿酸(SUA)水平。结果冠心病组尿酸水平高于非冠心病组。结论血清尿酸水平是糖尿病合并冠心病患者冠状动脉病变的危险因素。

Objective To investigate the relationship between serum level of uric acid and the coronary artery lesions in patients with coronary heart disease with type 2 diabetes. Methods Coronary angiography was performed in 88 patients with type 2 diabetes mellitus. These patients were divided into two groups according to the results of coronary angiography： coronary heart disease （ CHD ） group （ n = 52 ） and non - coronary heart disease group （non - CHD） （n = 56 ）. The CHD group includeed three subgroups according to the number of coronary artery involved：1 -branch ,2 - branch ,3 -branch. All the patients underwent examination of serum uric acid （ SUA ）. Results The serum level of uric acid of CHD group were higher than those in the non - CHD group. Conclusion The serum level of uric acid wast he risk factors of extent of coronary artery lesions in patients with coronary heart disease with type 2 diabetes.