CO_2冷冻治疗阴道残端复发性卵巢癌疗效观察——附一例报告

Effect of cryosurgery on recurrent ovarian cancer at vaginal residue:a report of one case

目的观察冷冻治疗阴道残端复发性卵巢癌的效果。方法经阴道冷冻阴道残端复发性卵巢黏液性癌1例,比较冷冻前后肿瘤组织病理学改变;定期复查记录瘤体变化;末次冷冻后1周剖腹行肿瘤细胞减灭术。结果冷冻前组织中见许多形态、结构完整的肿瘤细胞;冷冻后肿瘤组织细胞完全破碎,丧失一切正常结构;瘤体随着重复冷冻逐渐缩小,术后病理:"纤维结缔组织中见少许黏液腺癌浸润"。结论冷冻治疗阴道残端癌,可以有效地减灭肿瘤,操作简便,副作用少。冷冻可以与化疗。

Objective To observe the effect of cryosurgery on recurrent ovarian cancer at vaginal residue. Methods Cryosurgery via vagina was used to treat a patient diagnosed as recurrent mucinous ovarian cancer at vaginal residue. The pathological change was compared fore - and - after cryosurgery. The bulk of tumor was examined termly. The cytoreductive surgery was performed 1 week after last cryosurgery. Results Many cancer cells with intact figure and structure before cryosurgery was completely destroyed after cryosurgery and lost normal structure. The bulk of tumor was gradually reduced after cryosurgery. Pathological report showed a little mucinous adenocarcinoma among fibrous connective tissue. Conclusions Cryotherapy is an effective, convenient and less side - effect method to treat metastasis tumor at vagial residue. As part of integrative therapy, cryosurgery can be used to cure gynecologic tumor with chemotherapy and surgery.