新疆南疆地区嗜人T淋巴细胞病毒Ⅰ型血清流行病学调查

Serological survey of human T lymphotropic virus type Ⅰ (HTLV-1) IgG antibody in south region of Xinjiang

通过血清流行病学调查，了解人嗜Ｔ淋巴细胞病毒Ⅰ型（ＨＴＬＶ－１）在新疆南部（南疆）少数民族地区的流行情况。自南疆喀什、和田、阿图什地区采集正常人群中不同年龄组、不同民族的血清标本２６４２份，其中维吾尔族（维族）１０８２份，汉族１０８９份，柯尔克孜族（柯族）４７１份。用免疫荧光法（ＩＦＡ）检测上述血清中ＨＴＬＶ－１ＩｇＧ抗体，结果维族抗体阳性率为０．７４％（８／１０８２），汉族为０（０／１０８９），柯族为０．２１％（１／４７１）。

Human T lymphotropic virus type-1 (HTLV-1) is endemic in southwestern Japan, Seychelles Islands, Caribbean basin, Brazil, and Sub Saharan Africa. Recently, the prevalence of HTLV-1 of domestic source has been reported from Beijing, Fujian and so forth. The object of our study is to know whether the prevalence of HTLV-1 is present in Xinjiang. We collected 2642 serm samples of various ages and different nationalities (Uigur, Han and Khalkhas) from south region of Xinjiang and tested for determination of HTLV-1 IgG antibody by IFA. The results showed that the total positive rate of HTLV-1 IgG was 0.34% (9/2642), of which Uigur nationality was 0.74% (8/1082), Khalkhas nationality was 0.21 (1/471), Han nationality was zero (0/1089). This data indicated that there are HTLV-1 infection among the population of Xinjiang and especially in Uigur and Khalkhas. Why did the minority nationalities have relatively high frequency of HTLV-1 infection? This needs to be studied further