摘要
甲状腺相关眼病(TAO)发病率较高,严重影响患者的生活质量,治疗效果欠佳,早期诊断和寻求有效的治疗方法具有重大的临床价值。发现下丘脑-垂体-甲状腺轴功能紊乱和自身免疫异常是诊断TAO的关键。抗甲状腺药物、手术和131I三种治疗方法对眼病无影响。单纯性突眼无需特殊处理,轻度浸润性突眼建议随访,中、重度活动性浸润性突眼可选用甲泼尼龙冲击治疗和眼眶放疗,必要时可选用生长抑素的类似物或其他免疫抑制剂治疗。
Thyroid associated ophthalmopathy （TAO） has a high incidence. It can affect patient＇s quality of life and it is difficult to cure. So it has a great chnical value to diagnosis early and seek an effective therapoutic method. It＇s very important for diagnosis to find functional disorder of hypothalamic-pituitary-thyroid axis and immunologic abnormality. Antithyroid drugs, thyroidectomy and radioiodine have no harm to TAO. A wait-and-see policy is recommended in mild TAO. Moderate or severe TAO is recommended to use intravenous methylprednisolone and orbital radiotherapy. Somatostatin analogs or other immunosuppressive therapy can be used when glucocorticoid and orbital radiotherapy have no effects.
出处
《医学综述》
2008年第12期1840-1842,共3页
Medical Recapitulate
关键词
甲状腺相关眼病
诊断
治疗
Thyroid associated ophthalmopathy
Diagnosis
Therapy
