摘要
目的:研究紫葳科角蒿属植物大花鸡肉参的化学成分。方法:利用硅胶色谱柱,制备薄层色谱和葡聚糖凝胶Sephadex LH-20柱纯化,硅胶柱色谱进行分离纯化,通过理化常数和光谱分析鉴定化合物的结构。结果:从大花鸡肉参的乙醇提取物中分离并鉴定了12个化合物的结构,分别是:邻-羟基苯甲酸(O-Hydroxybenzoic acid)、棕榈酸(Palmitic acid)、正二十六烷酸(Hexacosanoic acid)、β-谷甾醇(β-Sitosterol)、β-胡萝卜苷(Daucosterol)、齐墩果酸(Oleanolic acid)、乌苏酸(Ursolic acid)、槲皮素(Quercetin)、槲皮苷(Vincetoxicosi-de B)、对羟基苯甲酸(p-Hydroxy benzoic acid)、3-甲氧基-4-羟基苯甲酸(3-Methoxy 4-hydroxy-benzoic acid)、豆甾醇(Stigmasterol)。结论:化合物1-12均为首次从该植物中分离得到。
Objective: To study the chemical constituents of Incarvillea mairei var. granditlora (Wehrhahn) Grierson. Methods: Isolation and purification were carried out by macroporous absorption resin and silica gel column chromatography, and twelve compounds were identified by spectral and chemical methods. Results:Twelve compounds were obtained from alcohol extract and were determined as o-hydroxy benzoic acid, palmitic acid, hexacosanoic acid, β-sitosterol, daucosterol, oleanolic acid, ursolic acid, quercetin, vincetoxicoside B ,p-hdroxy benzoic acid,3-mthoxy 4-hydroxy-benzoic acid, sgmasterol. Conclusion:All of 12 compounds were obtained from the plant for the first time.
出处
《药学实践杂志》
CAS
2008年第3期166-168,171,共4页
Journal of Pharmaceutical Practice
基金
国家"863"计划(2006AA02Z338)
中国博士后科学基金(20070410711)
关键词
紫葳科角蒿属
大花鸡肉参
化学成分
提取方法
Incarvillea mairei var
granditlora (Wehrhahn) Grierson
chemical constituents
extraction