羧酸和乙酸酐合成甲基酮的研究

Synthesis of Methyl-ketone Compounds by Carboxylic Acid and Acetic Anhydride

酮是化学化工行业应用广泛的重要中间体,其常见的合成方法这些年来不断有新的报道。文章研究了以常见的羧酸和乙酸酐为起始原料合成甲基酮的方法。该方法实施简单,产物收率62%～89%,为酮提供了一种未见文献报道的合成新方法。

Ketone-compounds are important intermediate widely used in chemistry and chemical industry, their synthesis methods have reported continuously. A new method for the syntheses of methyl-ketone compounds using the carboxylic acid as starting material by condensation reaction with acetic anhydride was researched. This reaction was easy to be carried out and the yields were 62 %~89 %, which supplied a new synthesis method to ketone-compounds.