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重症监护病房细菌耐药性分析 被引量:1

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摘要 目的了解重症监护病房(ICU)的细菌耐药状况。方法对本院ICU2005年1月-2007年12月所分离的菌株进行分析。结果发病后4~21天疑似共分离细菌210株,革兰阴性杆菌占69.5%,革兰阳性球菌占30、5%;铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌、凝固酶阴性的葡萄球菌是最常见菌,革兰阴性杆菌对亚安培南、头孢他啶、含酶抑制剂的复合药物敏感性较高,革兰阳性球菌对万古霉素、氯霉素、左氧氟沙星敏感性较高;产超广谱β-内酰胺酶的大肠埃希菌和肺炎克雷伯菌株的检出率分别为17.1%和25.0%;屎肠球菌对青霉素、氨苄西林及高浓度庆大霉素的耐药率明显高于粪肠球菌;肺炎链球菌对青霉素的耐药率为20.0%;甲氧西林耐药金黄色葡萄球菌(MRSA)的检出率为60.0%,甲氧西林耐药的凝固酶阴性的葡萄球菌(MRCNS)检出率为77.8%,未发现糖肽类抗生素耐药的葡萄球菌。结论ICU的分离菌菌种分布有自己的特点,菌株耐药情况比较严重,应根据细菌耐药监测,指导临床合理使用抗菌药物以控制耐药菌的产生。
出处 《河南职工医学院学报》 2008年第3期280-283,共4页 Journal of Henan Medical College For Staff and Workers
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