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舒芬太尼用于防治瑞芬太尼复合麻醉术后急性疼痛 被引量:2

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摘要 目的评估舒芬太尼在减轻以瑞芬太尼进行静吸复合全身麻醉后急性疼痛的临床疗效。方法60例择期行腹腔镜下胆囊切除术的患者,随机分为舒芬太尼组(SF组)、芬太尼组(F组)和曲马多组(T组),每组各20例。手术结束前10min,SF组静脉注射舒芬太尼0.15μg/ks,F组静脉注射芬太尼1.5μg/kg,T组静脉注射曲马多1.5mg/kg。记录并比较三组苏醒后的视觉模拟评分(VAS)、镇静评分、舒适评分和不良反应发生例数。结果SF组患者拔管后10、30、60min的VAS分别为(1.38±1.74)分、(1.28±1.01)分、(1.15±1.10)分,较F、T组低(P〈0.05);SF组各时间点的舒适评分、镇静评分较F、T组高(P〈0.05);T组恶心、呕吐的发生率(35.0%、25.0%)高于sF、F组(P〈0.05);F组呼吸抑制的发生率(25.0%)高于SF、T组(P〈0.05)。结论舒芬太尼在控制瑞芬太尼麻醉术后急性镇痛中的效果较芬太尼、曲马多更佳,具有不良反应少、舒适度高的优点。
出处 《中国医师进修杂志》 2008年第6期31-33,共3页 Chinese Journal of Postgraduates of Medicine
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  • 1刘建华,沈金美,李李,常业恬.瑞芬太尼丙泊酚全凭静脉麻醉与静吸复合麻醉用于腹腔镜胆囊切除术的比较[J].中国新药杂志,2006,15(3):222-224. 被引量:31
  • 2吴晓平.缝合切口时应用曲马多的术后疗效[J].中国医师进修杂志(外科版),2006,29(10):59-60. 被引量:4
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