肿瘤微转移研究的临床意义

Clinical significan of micrometastasis in cancer

微转移是肿瘤患者一个独立的预后因素，无瘤生存率和整体生存率都与微转移有关。微转移还可用于判断肿瘤转移和复发，评估肿瘤患者对于辅助治疗的效果，预测患者预后以及提高肿瘤患者肿瘤分期，对指导临床综合治疗均具有重要价值。对微转移的研究还存在一些问题，如缺少回顾性分析，研究的病例过少，以及随访时间过短等都限制了目前对微转移临床意义的研究。

Micrometastasis is an independable prognostic factor for the cancer patients. Furthermore, free-disease survival and overall survival of the cancer patients are correlated with micrometastasis. In addition, detection of micrometastasis can be used to monitor the efficacy of adjuvant therapy, predict outcome and improve the stage of patients with carcinoma. Micrometastasis has great significance for clinical comprehensive treatment. The limitations of this study include the lackness of retrospective analysis, the small number of pa- tients studied, and the short follow-up time for the cancer patients.