期刊文献+

鼻内镜下^(125)I粒子植入治疗鼻咽癌放疗后鼻咽部残留病灶 被引量:2

Iodine-125 seeds interstitial brachytherapy guided by nasal endoscopy for residue of nasopharyngeal carcinoma after radiotherapy
下载PDF
导出
摘要 目的对放疗后鼻咽部仍有残留病灶的鼻咽癌患者行鼻内镜引导下放射性125I粒子植入术的临床应用进行评估。方法鼻内镜引导下予32例放疗后鼻咽部仍有残留病灶的鼻咽癌患者行125I粒子植入术。结果全组完全缓解10例,部分缓解18例,总有效率为87.6%。5年生存率为68.8%。未出现严重并发症。结论鼻内镜引导下放射性125I粒子植入术对鼻咽癌放疗后鼻咽部残留病灶有较好的疗效,且并发症少。 [Objective] To make an estimate of clinical practice of iodine-125 seeds interstitial brachytherapy guided by nasal endoscopy for the residue of nasopharyngeal carcinoma after radiotherapy. [Methods] 32 patients with residue of nasopharyngeal carcinoma after radiotherapy were treated with iodine-125 seeds brachytherapy guided by nasal endoscopy. [Results] Of the 32 patients, 10 cases got complete response, 18 cases got partial response, and the overall response rate was 87.6%. The 5-year survival rate was 68.8%. No serious complications was found in this group. [Conclusions] Iodine-125 seeds interstitial brachytherapy guided by nasal endoscopy has better efficacy and fewer complications in the treatment of the residue of nasopharyngeal carcinoma after radiotherapy.
出处 《中国内镜杂志》 CSCD 北大核心 2008年第5期485-486,490,共3页 China Journal of Endoscopy
关键词 鼻内镜 ^125Ⅰ粒子 鼻咽癌 nasal endoscopy iodine-125 seeds nasopharyngeal carcinoma
  • 相关文献

参考文献6

二级参考文献45

  • 1谢大业,沈坤炜,夏长华.肺癌规范性手术及术中组织间放疗[J].现代诊断与治疗,1994,5(4):203-205. 被引量:12
  • 2俞炎平,郑家平,邵国良,狄小云,胡福军.CT引导下^(125)I粒子永久植入治疗难治性恶性肿瘤[J].中国肿瘤,2005,14(4):278-280. 被引量:10
  • 3Bonadeo FA, Vaccaro CA, Benati ML, et al, Rectal cancer: local recurfence after surgery without radiotherapy. Dis Colon Rectum,2001, Mar;44(3) :374- 379.
  • 4Kapiteijin E, Velde C. European trials with total mesorectal excision. Semin Surg Oncol,2000,19 (4) :350-357.
  • 5Mayr MT, Crocker L, Butker EK, et al. Resuhs of interstititial brachytherapy for malignant brain tumors. Inter J Onco1,2002,21:817-823.
  • 6Critz FA, Levinson AK, Williams WH. et al. Simultaneous radiotherapy for prostate cancer: ^125I prostate implant foUowed by external - beam radiation. Cancer J Sci Am,1998 ,Nov - Dec,4(6) :347-348.
  • 7Sekimoto M,Monden T,Tomita N. et al. A case of local recurrence of rectal cancer that achieved a complete response with high - dose instititial brachytherapy. Gan To Kagaku Ryoho, 1997,24( 12 ) : 1848-1850.
  • 8Alektiar KM,Zelefsky MJ,Paty PB,et al. High -dose -rate intraoperatire brachytherapy for recurrent colorectal cancer. In J Radiat Oncol Biol Phys,2OO0,Aug 1,48( 1 ) :219 -226.
  • 9Beyer DC, Puente F, Rogers KL, et al. Prostate brachy therapy: comparison of dose distribution with different 125Ⅰ source designs[J]. Radiology, 2001, 221 (3) :623.
  • 10Ankem MK, DeCarvalho VS, Harangozo AM, et al. Implications of radioactive seed migration to the lungs after prostate brachytherapy[J]. Urology, 2002,59 (4): 555.

共引文献99

同被引文献19

  • 1黄金华,顾仰葵,张亮,张福君,范卫君,赵明,李传行.鼻咽癌肺转移瘤^(125)I放射性粒子植入疗效分析[J].国际肿瘤学杂志,2006,33(3):233-235. 被引量:8
  • 2张相民,蓝小林,吴修洪,张群贵,王勇斌,叶永强.鼻咽癌放疗后鼻窦炎的特点及处理[J].中国耳鼻咽喉头颈外科,2006,13(6):381-383. 被引量:14
  • 3王成涛,曹卡加,李茵,谢国丰,黄培钰.鼻咽癌远处转移的预后因素分析[J].癌症,2007,26(2):212-215. 被引量:23
  • 4Xu T, Tang J, Gu M, et al. Recurrent nasopharyngeal carcinoma: a clinical dilemma and challenge[J].Curr Oncol.2013, 20(5):406-419.
  • 5Tian Y, Xie Q, Tian Y, et al. Radioactive 125I seed inhibits the cell growth, migration, and invasion of nasopharyngeal carcinoma by triggering DNA damage and inactivating VEGFA/ERK signaling[J]. PLoS One, 2013, 8(9): e74038.
  • 6Li HX, Zhao J, Shen K, et al. Comparison of Iodine125 seeds implantation and afterloading radiotherapy in murine models of human cervical cancer[J].Arch Gynecol Obstet.2014, 289(5):1101-1106.
  • 7Stoker SD, van Diessen JN, de Boer JP, et al. Current treatment options for local residual nasopharyngeal carcinoma[J].Curr Treat Options Oncol.2013, 14(4):475-491.
  • 8Jiang YL, Meng N, Wang JJ, et al. CTguided iodine125 seed permanent implantation for recurrent head and neck cancers[J]. Radiat Oncol, 2010, 30(5): 68.
  • 9Zhang F, Wu K, Gao F, et al. Refractory nasopharyngeal carcinoma: positron emission tomography combined with computed tomographyguided 125I seed implantation therapy after repeated traditional radiochemotherapy[J].Otolaryngol Head Neck Surg.2013, 149(3):417-423.
  • 10Rosenblatt E, AbdelWahab M, ElGantiry M, et al. Brachytherapy boost in locoregionally advanced nasopharyngeal carcinoma: a prospective randomized trial of the International Atomic Energy Agency[J].Radiat Oncol.2014, 9(1):67-.

引证文献2

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部