摘要
目的研究本室制备的人角膜接触镜材料的生物性能。方法采用细胞毒性试验、红细胞溶血试验以及蛋白质沉积试验方法。结果所制备的人角膜接触镜材料对人胚肺纤维细胞(HEFC)毒性评价为1级无毒性;红细胞溶血率为1.62%合格;在体温范围内抗蛋白质沉积作用较好。结论本室制备的人角膜接触镜材料具有较好的生物相容性。
Objective To study the biocompatibility of contact lens material for human cornea prepared in our department. Methods Biological properties of the material were assessed by cytotoxicity, haemolysis and protein aggradation. Results The material had no toxicity for HEFC. The haemolysis rate was eligibility( 1.62% ). Anti-protein-aggradation was quite good. Conclusion The contact lens material by our department possesses quite good biological properties.
出处
《中华生物医学工程杂志》
CAS
2007年第5期317-319,共3页
Chinese Journal of Biomedical Engineering
基金
国家自然科学基金(29976007)
关键词
角膜
接触镜
水凝胶
细胞毒性
溶血
蛋白质沉积
Cornea
Contact lens
Hydrogel
Cell toxicity
Haemolysis
Affinities of protein