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人角膜接触镜材料生物相容性的研究 被引量:1

Studies on biocompatibiUty of contact lens material for human cornea
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摘要 目的研究本室制备的人角膜接触镜材料的生物性能。方法采用细胞毒性试验、红细胞溶血试验以及蛋白质沉积试验方法。结果所制备的人角膜接触镜材料对人胚肺纤维细胞(HEFC)毒性评价为1级无毒性;红细胞溶血率为1.62%合格;在体温范围内抗蛋白质沉积作用较好。结论本室制备的人角膜接触镜材料具有较好的生物相容性。 Objective To study the biocompatibility of contact lens material for human cornea prepared in our department. Methods Biological properties of the material were assessed by cytotoxicity, haemolysis and protein aggradation. Results The material had no toxicity for HEFC. The haemolysis rate was eligibility( 1.62% ). Anti-protein-aggradation was quite good. Conclusion The contact lens material by our department possesses quite good biological properties.
出处 《中华生物医学工程杂志》 CAS 2007年第5期317-319,共3页 Chinese Journal of Biomedical Engineering
基金 国家自然科学基金(29976007)
关键词 角膜 接触镜 水凝胶 细胞毒性 溶血 蛋白质沉积 Cornea Contact lens Hydrogel Cell toxicity Haemolysis Affinities of protein
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  • 2黎新明,崔英德,尹国强,廖列文,贾振宇,张翠荣.水凝胶接触镜材料与三油酸甘油酯的亲合性[J].桂林工学院学报,2006,26(2):268-270. 被引量:2
  • 3杨晓莉,王淮庆,胡俊,王玲.彩色角膜接触镜材料的制备[J].化工时刊,2007,21(1):1-2. 被引量:1
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  • 6Myers R,Larsen D,Tsao M,et al.Quantity of protein deposited on hydrogel contact lenses and its relation to visible protein deposits[J].Optom Vis Sci,1991,(68):776-183
  • 7Mark Van Beeka,Lyndon Jones,Heather Sheardown.Hyaluronic acid containing hydrogels for the reduction of protein adsorption[J].Biomaterials,2008,(29):780-789.
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