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雷帕霉素对大鼠缺血再灌注肾超微结构和凋亡蛋白表达的影响 被引量：1

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作者 郑传东 苟欣 杨华安 刘莉 蒲晓峰 何卫阳
机构地区 重庆医科大学：附属第一医院泌尿外科 重庆医科大学：基础医学院病理学教研室
出处 《第三军医大学学报》 CAS CSCD 北大核心 2008年第13期1226-1226,1230,共2页 Journal of Third Military Medical University
基金 重庆市卫生局科研基金(05-2-186)~~
关键词 再灌注损伤 雷帕霉素 超微结构 FAS BCL-2
分类号 R619.9 [医药卫生—外科学]
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参考文献6

二级参考文献24

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共引文献26

同被引文献34

  • 1张俊峰,陈规划,陆敏强,蔡常洁,杨扬,李华,易慧敏.雷帕霉素诱导人肝癌细胞BEL-7402凋亡中Bcl-2作用研究[J].中华肿瘤防治杂志,2006,13(19):1445-1448. 被引量：8
  • 2马湘一,王世宣,刘琰,刘荣华,卢运萍,马丁.雷帕霉素联合紫杉醇诱导卵巢癌细胞A2780和SKOV3凋亡及其分子机制[J].癌症,2007,26(4):367-370. 被引量：12
  • 3Kumar A et al. Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole body glucose and lipid metabolism. Diabetes, 2010, [Epub ahead of print].
  • 4Kenerson HL et al. Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors. Cancer Res, 2002, 62:5645-5650.
  • 5Koh PO et al. Estradiol attenuates the focal cerebral ischernic injury through mTOR/pTOS6 kinase signaling pathway, .Neurosci Lett, 2008, 436:62-66.
  • 6Kofulska K et al. Cardiac rhabdomyomas in tuberous sclerosis complex show apoptosis regulation and roTOR pathway abnormalities. Pediatr Dev Pathol, 2009, 12:89-95.
  • 7Kimura R et al. Glucagon-like peptide-1 (GLP-1) protects against methylglyoxal-induced PC12 cell apoptosis through the PI3K/Akt/mTOR/GCLc/redox signaling pathway. Neuroscience, 2009, 162:1212-1219.
  • 8Gu L et al. Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting roTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis. Leukemia, 2008, 22:2091-2096.
  • 9Opel D et al. Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug- induced apoptosis. Cancer Res, 2008, 68:6271-6280.
  • 10Lafay-Chebassier C et al. The immunosuppressant rapamycin exacerbates neurotoxicity of A beta peptide. J Neurosci Res, 2006, 84:1323-1334.

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二级引证文献64

第三军医大学学报
2008年 第13期

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