蛛网膜下腔出血后血浆不对称二甲基精氨酸的含量研究

Research on asymmetrical dimethylarginine in blood plasma after subarachnoid hemorrhage

研究血浆中不对称二甲基精氨酸(ADMA)浓度与蛛网膜下腔出血(SAH)的关系。蛛网膜下腔出血患者血浆ADMA平均水平,第3、7和14天分别为2.3±0.8μmol/L、6.44±1.5μmol/L和4.1±0.9μmol/L,对照组平均为1.1±0.3μmol/L,两组间比较差异显著(P<0.01)。ADMA参与了蛛网膜下腔出血病理生理过程,水平与脑血管痉挛关系密切。

To investigate the relations of the consistency of asymmetrical dimethyl-arginine （ADMA） in plasm after subarachnoid hemorrhage（SAH）. The average plasm consistency of ADMA in SAH cases in 3, 7 adn 14 d is 2.3±0.8μmol/L, 6.4±1.5μmol/L, 4.1±0.9μmol/L, while in control group is 1.1±0.3 mol/L. There is a remarkable difference in the two groups （P〈0.01）.