儿童急性淋巴细胞白血病诱导缓解期院内感染51例临床分析

Clinical analysis of 51 children with acute lymphoblastic leukemia suffered infection in hospital during induction remission

目的:研究儿童急性淋巴细胞白血病(Acute lymphoblastic leukemia,ALL)诱导缓解期间院内感染发生相关因素。方法:分析51例儿童ALL接受诱导缓解治疗期院内感染的临床资料。结果:化疗中患儿均发生院内感染,中性粒细胞减少时感染不易控制。常见感染部位为呼吸道、消化道和皮肤粘膜,结论:病原学检查阳性率低,儿童ALL院内感染死亡率低于成人。

Objective：To explore the correlation factors of children with acute lymphocytic leukemia （ALL） suffered infection in hospital during induction remission. Methods：The clinical data of 51 children with ALL suffered infection in hospital during induction remission were analyzed. Results：All the 51 patients got infected, the infection in patients who suffered neutropenia were hard to control. The infections commonly occurred in respiratory and digestive system,skin or mucous. Conclusion：Positive results of etiology were uncommon,and mortality of children is less than that of adult.