紫杉醇联合小剂量5-氟尿嘧啶和奥沙利铂治疗晚期胃癌36例疗效观察被引量：2

Paclitaxel plus low dose of 5-fluorouracil and oxaliplatin combination chemotherapy in the treatment of advanced gastric carcinoma

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摘要目的观察紫杉醇(PTX)联合小剂量5-氟尿嘧啶(5-FU)和奥沙利铂(L-OHP)治疗晚期胃癌的疗效。方法选择36例晚期胃癌进行为期2年的观察。结果该疗法对晚期胃癌总的肿瘤控制率(CR+PR+SD)为83.3%。近期有效率(CR+PR)为50.0%。结论PTX联合小剂量5-FU和L-OHP治疗晚期胃癌的疗效较好,不良反应可以耐受,值得深入研究。 Objective To evaluate the efficacy of paclitaxel plus low dose of 5-fluorouracil （5-FU） and oxaliplatin （L-OHP） combination chemotherapy in the treatment of advanced gastric carcinoma. Methods Advanced gastric carcinoma （36 cases） was treated by paclitaxel plus low dose of 5-FU and L-OHP combination chemotherapy. The 36 patients were observed for 2 years. Results After treatment, the tumor controlrate （CR＋PR＋SD） was83.3%; effective rate （CR＋PR） inthe nearfuture was50. O%. Conclusions Paclitaxel plus low dose of 5-FU and L-OHP combination chemotherapy in the treatment of advanced gastric carcinoma is effective and tolerable. It is worth studing in the future.

作者刘国建朱春平林岩吴国远

机构地区南京市第三医院肿瘤科

出处《中国厂矿医学》 2008年第3期278-279,共2页 Chinese Medicine of Factory and Mine

关键词胃肿瘤晚期紫杉醇 5-氟尿嘧啶奥沙利铂 Advanced gastric carcinoma Paclitaxel 5-fluorouracil Oxaliplatin

分类号 R735.2 [医药卫生—肿瘤] R730.35 [医药卫生—肿瘤]

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