依达拉奉对急性脑梗死的疗效观察

Clinical efficacy of edaravone on acute cerebral infarction

目的观察依达拉奉对急性脑梗死的治疗效果。方法将80例脑梗死患者随机分为治疗组和对照组。对照组给予常规治疗,治疗组在常规治疗的基础上,给予依达拉奉30 mg+5%葡萄糖或生理盐水100mL静脉滴注,30 min内滴完,每日2次,共14 d。治疗组于治疗前和治疗后第14天分别进行神经功能缺损评分及疗效评定。结果治疗14 d后,治疗组神经功能缺损评分为(9.2±5.8)分,明显低于对照组的(15.4±6.6)分;治疗组的显效率和有效率分别为52.4%和90.5%,显著高于对照组的36.3%和78.1%。结论依达拉奉可促进脑梗死患者的神经功能康复。

Objective To evaluate the efficacy of edaravone on acute cerebral infarction. Methods 80 cases were divided into treatment group and control group randomly. Neurological functional deficit scores were utilized for assessment before treatment. On the 14th day after treatment, the scores and efficacy of the patients were assessed again. Results After 14 d, the neurological functional deficit scores of treatment group was （9.2 ± 5.8）, and it was （ 15.4 ± 6.6） in the control group. There were significant differences between the two groups（ P 〈 0.05）. There were also signif- icant differences between the two groups in terms of apparent effective rates （treated group： 52.4% ; control group： 31.3 %, P 〈 0.05） and improvement rates （ treated group： 90.5 % ; control group 78.1%, P 〈 0.05 ）. Conclusion Edaravone can accelerate the recovery of neural function after cerebral infarction.