培氟沙星治疗急性盆腔炎的临床研究

Therapeutic effect of Pefloxacin injection on acute pelvic inflammatory disease

目的评价国产培氟沙星治疗急性盆腔炎的疗效。方法选择符合诊断标准的患者34例,随机分为2组:治疗组17例,给予培氟沙星0.4 g+甲硝唑0.2 g,静脉滴注,2次/d;对照组17例,给予左氧氟沙星0.2 g+甲硝唑0.2 g,静脉滴注,2次/d。两组均治疗10 d。结果治疗组、对照组的痊愈率分别是64.71%、52.94%(P>0.05),临床总有效率分别为88.24%、70.59%(P>0.05)。结论在急性盆腔炎治疗中,国产培氟沙星注射液与左氧氟沙星注射液临床疗效相当,其安全性需进一步观察。

Objective To evaluate the effect of pefloxacin injection （made in China） on acute pelvic inflammatory disease. Methods Thirty four patients were randomly divided into treatment group （17 cases） and control group （17 casea）,The treatment group used pefloxacin injection and metronidazole injection, the control group used lev- ofloxacin injection and metronidazole injection. Results The curative rates of treatment group and control group were 64.71% and 52.94% （P 〉 0.0S）, and the overall clinical efficacy rates of them were 88.24% and 70.59% （P 〉 0.05）, Conclusion Pefloxacin injection has the same efficacy as levofloxacin in the treatment of acute pelvic inflammatory disease.