轻微病变肾病综合征的肾功能不全

RENAL INSUFFICIENCY IN MINIMAL CHANGE NEPHROTIC SYNDROME

12例轻微病变肾病综合征（MCNS）肾功能不全，血肌酐浓度124～257μmol／L（平均190±42μmol／L），经用速尿及强的松等治疗后，肾功能于7～150天（平均33天）恢复正常。MCNS肾功能不全发生率颇高（36％）应予关注。本研究提示：NCNS肾功能不全和液体潴留及肾实质水肿有关，用速尿及强的松可使之逆转。

Renal insufficiency with MCNS, serum creatinines, ranging from 125 to 257 μmol/L(190±42μmol/l,), was studied in 12 MCNS patients. Recovery of renal function occurred in all patients 7 to 150 days after administration of frusemide and prednisone. The incidence of renal insufficiency in MCN is so high that clinicians ought to pay a great attention to this field. The study suggests that renal insufficieny in MCNS may be related to fluid retention and intrarenal edema, and thatadministration of frusemide and prednisone often makes it reversible