摘要
目的探讨眼镜蛇毒对大鼠延髓c-fos表达的影响。方法采用免疫组织化学方法,观察并比较c-fos阳性细胞在眼镜蛇毒组、生理盐水组、正常对照组大鼠延髓中的表达。结果眼镜蛇毒组大鼠延髓外侧网状核c-fos阳性细胞明显多于生理盐水组和正常对照组(P<0.01)。结论眼镜蛇毒对大鼠延髓c-fos表达有上调作用。
Objective To investigate the effects of Naja naja atra venom on the expression of c-fos in medulla oblongata of rat. Methods The methods of immunohistochemistry technique were used to observe the different expression of c-fos positive cells in Naja naja atra venom group, saline group and control group. Results The number of c-fos positive cells in nucleus reticularis lateralis of Naja naja atra venom group were higher markedly than that of saline and control groups （P〈0. 01）. Conclusion Naja naja atra venom could increase the expression of c-fos in medulla oblongata of rats .
出处
《蛇志》
2008年第2期85-87,共3页
Journal of Snake
基金
皖南医学院中青年科研基金资助课题(项目编号:WK200706)
关键词
眼镜蛇毒
延髓
C-FOS
大鼠
Naja naja atra venom
Medulla oblongata
c-fos
Rat
