不同方法对糖耐量减低干预效果的比较研究

The Comparative Study of Intervention Effect by Different Methods on the Population with Impaired Glucose Tolerance

目的:比较不同干预方法对糖耐量减低的影响。方法:选取深圳市五个区IGT患者各100例,按照干预方案再分为对照组、饮食加运动组、阿卡波糖组、二甲双胍组和中药组各100例。分别于干预前后测定BMI、SBP、DBP、FPG、2hPG、HbA1C。结果:饮食运动组干预后FPG、2hPG与对照组干预后比较差异有统计学意义(P<0.05);阿卡波糖及二甲双胍组干预后FPG、2hPG、HbA1C均明显低于干预前、对照组、饮食运动组及中药组,其差异有统计学意义(P<0.05);中药组FPG、2hPG明显低于干预前及对照组,HbA1C低于对照组和饮食运动组,其差异有统计学意义(P<0.05)。结论:上述4种方法均有效降低血糖,尤以西药组突出。

Objective To evaluate the effect of different methods on the population with impaired glucose tolerance （IGT）. Methods The total of five hundred IGT patients were divided into five groups according to interventions. BMI, SBP, the follow up. Results DBP, FPG, 2hPG, HbAIC were determined before intervention and yearly during By the end of the study, although the FPG and 2hPG slightly decreased in diet plus exercise group, they were significantly lower than those in the were significantly decreased in Acarbose and Metformin group. 2hPG were significantly lower than those of baseline and in control group. In contrast, the FPG, 2hPG and HbAIC In traditional Chinese medicine group, the FPG and control group, at the same time, the HbAIC were significantly lower than those in the control and diet plus exercise group. Conclusion These four methods can effectively lower blood sugar, especially the western medicine groups.