无创正压通气治疗充血性心力衰竭疗效观察

The Effect of Noninvasive Positive-Pressure Ventilation for the Treatment of Congestive Heart Failure

目的:观察无创正压通气(NPPV)治疗充血性心力衰竭(CHF)的临床疗效:方法:90例CHF患者随机分为治疗组(60例)和对照组(30例),对照组采用常规CHF治疗,治疗组在对照组治疗基础上,给予NPPV治疗,记录治疗前、后患者的左室射血分数(LVEF),每分钟输出量(CO),每搏输出量(SV)并比较。结果:CHF患者的LVEF、CO、SV较健康组明显降低,应用NPPV治疗4d后,患者的LVEF、CO、SV较治疗前有明显增加,差异有显著性意义(P<0.05)。结论:采用NPPV可改善CHF患者的左心功能,提高临床疗效。

Objective To observe the effect of the treatment of noninvasive positive-pressure ventilation for the treatment of congestive heart failure. Methods Ninety patients with congestive heart failure were divided into two groups： conventional therapy group in which patients were given cardiotonics, diuretics, vasodilators, etc and NPPV group in which patients received noninvasive positive pressure ventilation in addition to conventional treatment. Left ventricular ejection fraction （LVEF）. cardiac output （CO）. stroke volume （SV） and clinical signs were observed before and after treatment. Results LVEF、CO、 SV in patients with congestive heart failure was significantly lower than that in the health. After 4-day＇s treatment, the clinical symptoms including LVEF、CO、 SV were distinctly improved in NPPV group （P 〈 0.05）. Conclusion Noninvasive positive pressure ventilation is one of the effective methods for the treatment of congestive heart failure.