期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

间充质干细胞免疫调节作用的研究进展 被引量：1

下载PDF
导出
摘要 干细胞是近年来研究的热点，骨髓中除血干细胞以外，还含有另一类干细胞——间充质干细胞（mesenchymal stem cells，MSC）。相差显微镜观察发现体外培养的MSC团与成纤维细胞类似，具有很强的自我增殖能力和多向分化潜能。传代培养时，MSC表现出高度的扩增能力，且仍保持着细胞的染色体核型和端粒活性。在不同的诱导条件下，具有向中胚层和神经外胚层组织细胞分化的能力，
作者 程书榜 王成友
机构地区 深圳市第二人民医院普通外科
出处 《深圳中西医结合杂志》 2008年第3期184-186,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
基金 2008年深圳市科技局一般资助项目
关键词 间充质干细胞 免疫调节 综述
分类号 R392.12 [医药卫生—免疫学]
  • 相关文献

参考文献16

  • 1Minguell J J, Eeices A, Conget E Mesenchymal stem cell[J]. Exp Biol Med, 2001, 226(6):507-520.
  • 2Barry FP, Murphy JM. Mesenchymal stem cells:clinical applications and biological characterization [ J]. Int J Biochem Cell Biol, 2004, 36:5682584.
  • 3Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stern cells [J]. Science, 1999, 284:1432147.
  • 4Erices A, Conget P, minguell JJ. Mesenchymal progenitor cells in human umbilical cord blood[J]. Br J Haematol, 2000, 109(1):235.
  • 5Haynesworth SE, Baber MA, Caplan AI. Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies [J]. Bone, 1992, 13:69.
  • 6Tse ET, Pendleton JD, Beyer WM, et al. Suooreession of allogeneic T-cell proliferation by human marrow stremal cells: Implications in transplantation[J]. Transplantation, 2003, 75:389.
  • 7Gotherstrom C, Reinden O, Tammik C, et al. Immunological properties of human fetal mesenchymal stem cells [J]. Am J Obst Gynecol, 2003, 31:890.
  • 8Maitra B, Szekely E, Gjini K, et al. Mesenchymal stem cells:human mesenchymal stem cells sopport unrelated donor hematopoietic stem cells and support T-cell activation [ J ]. Bone marrow Traplantatioan, 2004, 33:597.
  • 9BartholomewA, Sturgeon C, Siatskas M, et al. Mesenchymal stem cells supress lymphocyte proliferation in vilro and prolong skin graft survival in vivo [J]. Exp Hematol, 2002, 30:42.
  • 10Di Nicola M, Carlo-stella C, Magni Me, et al/Human bone marrow stromal cells supress T- lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli[J]. Blood, 2002, 99:3838.

二级参考文献48

  • 1李宾公,曾秋棠,王红祥,邹萍,王庆海.脂肪来源与骨髓来源的基质干细胞的比较[J].中华器官移植杂志,2006,27(3):142-144. 被引量：13
  • 2王轩,杨甲梅,严以群,姚晓平,吴孟超.大鼠原位肝移植模型术式的改进[J].中华实验外科杂志,1997,14(1):59-60. 被引量：22
  • 3[1]Devine SM, Hoffman R. Role of mesenchymal stem cells in hematopoietic stem cell transplantation. Cur Opin Hematol, 2000;7: 358 - 363
  • 4[2]Friedenstein AJ, Chailakhyan RK, Gerasimov UV. Bone marrow osteogenic stem cells: in vitro cultivation and transplantation in diffusion chambers. Cell Tissue Kinet, 1987; 20:263- 272
  • 5[3]Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science, 1999; 284(5411): 143 - 147
  • 6[4]Deans RJ, Moseley AB. Mesenchymal stem cells: Biology and potential clinical uses. Exp Hematol, 2000; 28: 875 - 884
  • 7[5]Klyushnenkova E, Mosca J, McIntosh K. Human mesenchymal stem cells suppress allergenic T cell responses in vitro: implications for allergenic transplantation. Blood, 1998; 92:642a
  • 8[6]McIntosh K, Klyushnenkova E, Shustova V, et al. Suppression of alloreactive T cell response by human mesenchymal stem cells involves CD8+ cells. Blood, 1999; 94:133a
  • 9[7]Bartholomew A, Sturgeon C, Nelson M, et al. Allergenic mesenchymal stem cells have significant immunosuppressive activity.Exp Hematol, 1999; 27:123a
  • 10[8]Le Blanc K, Tammik C, Sundberg B, et al. Inhibition or enhancement of mixed lymphocyte cultures by allogeneic and autologous mesenchymal stem cells is dependent on cell dose. The 43rd annual meeting of american society of hematology in 2001

共引文献44

同被引文献38

引证文献1

二级引证文献2

深圳中西医结合杂志
2008年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部