慢性肾衰患者血清转铁蛋白受体的研究

Study of Serum Transferrin Receptor of Chronic Renal Failure

目的探讨血清转铁蛋白受体(sTfR)在慢性肾功能衰竭(CRF)伴缺铁性贫血患者中的意义。方法对60例CRF患者,20例健康对照者进行血红蛋白(Hb)、红细胞压积(Hct)、血清铁(SI)、血清铁蛋白(SF)、sTfR测定。结果sTfR在CRF伴缺铁组明显升高;与CRF不伴缺铁组比较有显著性差异(P<0.01)。结论血清sTfR含量能更加快速、真实地反映体内铁贮存情况,对患者的诊断、治疗具有重要意义。

Objective To study the significance of serum transferrin receptor（sTfR） of chronic renal failure （CRF） accompanied by iron deficiency anemia （IDA）. Methods To determine the levels of hematoglobin and hematocrit, serum iron, serum ferritin, and sTfR in 60 patients and 20 health controls,respectively. Results The level of sTfR in patients with C RE accompanied by IDA was significantly higher than that in patients with CRE alone （P 〈 0. 01 ） . Conclusion The level of serum sTfR can quickly and exactly reflect the condition of iron storage in the body and is helpful in the diagnosis and treatment of CRF.