期刊文献+

他汀类药物的多向性效应研究进展 被引量:5

下载PDF
导出
摘要 他汀类药物已广泛应用于临床主要用于调节血脂,近年来许多临床及实验研究证实这类药物还有抗炎、改善内皮功能、刺激骨形成、改善认知、抗肿瘤等作用,均对疾病的治疗可能产生深远的意义。现对这类药物作用的多向性效应做一总结。
作者 杜景霞
出处 《科教文汇》 2008年第18期200-200,205,共2页 Journal of Science and Education
  • 相关文献

参考文献11

二级参考文献121

  • 1[1]Steven RC, Douglas CB. Do statins prevent both cardiovascular disease and fracture? JAMA,2000,283: 3255-3258.
  • 2[2]Faber D. Cholesterol drugs show promise as bone builders. Science,2000,288:22.
  • 3[3]Mundy G, Greet R, Harris S, et al. Stimulation of bone formation invitro and in rodents by statins. Science,1999,286(3) :1946-1949.
  • 4[4]Gowen M, Mundy GR. Actions of recombinant interleukin 1, interleukin2, and interferon-gamma on bone resorption in vitro. J.Immunol, 1986,136: 2478-2490.
  • 5[5]Traianedes K, Dallas MR, Garret IR, et al. 5-Lipoxygenase metabolitesinhibit bone formation in vitro. Endocrinology, 1998,139: 3178-3180.
  • 6[6]Marcell CA, Yates JP, Mundy GR. in vivo effects of human recombi-nant transforming growth factor beta on bone turnover in normal mice. JBone Miner Res, 1990,5:1087-1089.
  • 7[7]Chan KA, Andrade SE, Boles M, et al. Inhibitors of hydroxymethyl-glutaryl-coenzyme A reductase and risk of fracture among older women.Lancet, 2000,355: 2185-2188.
  • 8[8]Wang P, Solomon DH, Hogun H, et al. HMG-CoA reductase inhibitorsand the risk of hip fractures in elderly patients. JAMA, 2000,283:3211-3216.
  • 9[9]Edwards CJ. Oral statins and increased bone-mineral density in postm-enopausal women. Lancet, 2000,355: 2218-2219.
  • 10[10]Rossouw JE, Lewis B, Rifkind BM, et al. The value of lowering chol-esterol after myocardial infarction. N Engl J Med, 1990, 323: 1112-1114.

共引文献26

同被引文献41

引证文献5

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部