摘要
为在细胞学水平进一步了解免疫细胞和喉癌细胞间的相互关系，对12例喉鳞状细胞癌病树活检组织进行了光、电镜观察。光镜观察发现瘤体内免疫细胞浸润少，免疫细胞主要位于瘤体周边与正常组织交界处，主要为淋巴细胞，少数为浆细胞，部分病例可见嗜酸性白细胞及少数肥大细胞。电镜下发现免疫细胞和癌细胞之间有三种毗邻关系：①癌细胞团被大量免疫细胞包绕；②癌细胞团周围有少许免疫细胞；③单个或少数癌细胞被免疫细胞包绕，癌细胞发生退变。提示增强局部免疫应能增强宿主对喉癌的抑制作用。
Twelve patients with squamous cacinoma of the larynx were investigatedhistopathologically and electromicroscopically. We found that lots of immune cells werearound the tumor-host interface, whereas the stromal and parenchymal infiltration werepoor; On the other hand, we found three relationship between the immune cells and thecancer cells, under transmission electron microscope. (1) Some cancer cell masses weresurounded by a large number of immune cells. (2) Others had very few immune cellsaround. (3) Only those cancer cells that were surrounded by lots of immune cells underwent degeneration.
出处
《耳鼻咽喉（头颈外科）》
1997年第6期362-365,共4页
Chinese Arch Otolaryngology-Head Neck Surg
基金
博士后科学基金
关键词
喉肿瘤
癌
免疫细胞
电镜
Laryngeal neoplasms
Carcinoma
Immunity，cellular
