摘要
在鲑鱼降钙素的合成中，采用空气氧化、二甲亚砜三氟乙酸氧化、二甲亚砜水氧化和铁氰化钾氧化四种方法，对二硫键的形成方法进行了比较．实验结果表明用铁氰化钾法氧化时间短。
The disulfide bond of salmon calcitonin was formed by employing air oxidation,DMSO/TFA oxidation,DMSO/H 2O oxidation and potassium ferricyanide oxidation.It seemed that the potassium ferricyanide oxidation method was superior to other methods in less reaction time and higher oxidation yield.
出处
《中国药物化学杂志》
CAS
CSCD
1997年第4期294-296,共3页
Chinese Journal of Medicinal Chemistry
关键词
鲑鱼降钙素
药物
二硫键
合成
salmon calcitonin
disulfide
oxidation
potassium ferricyanide
