西替考马中间体的合成及其在GC-MS分析中分子内的脱水行为

Synthesis of Intermediate for Centchroman and its Intramolecular Dehydration in the Process of GCMS

合成了２甲基３苯基４（２羟基４甲氧基）苯丁烯醇２，并对其进行了ＧＣＭＳ分析．结果在ＥＩＭＳ（７０ｅＶ）条件下具有２８４（５％）分子离子峰；进行ＧＣＭＳ分析时，当选择起始温度Ｔ＝１００℃，升温速度为３０℃／ｍｉｎ条件时，于６３ｍｉｎ分离出产物，并显示有２６６（１０％）的分子离子峰．

2Methyl3phenyl4(2hydroxy4methoxy)phenylbutene2ol was shown to have a molecular ion 284(5%) by means of EIMS(70 eV).It was found that in the process of GCMS,with the starting temperature T=100℃,heating rate=30℃/min and in time of 63 min.This compound had a molecular ion 266(10%),which resulted from the inner molecular dehydration.