磁共振灌注成像对肝癌介入治疗疗效评价

Value of MR Perfusion Imaging after Interventional Treatment of Liver Cancer

目的:探讨PWI在评估肝癌介入治疗的局部疗效中的价值。方法:搜集36例肝癌患者,经肝动脉化疗栓塞及微波消融术后,行磁共振灌注成像,对比残留肿瘤与良性强化组织的量化结果,并评价灌注成像诊断准确性。结果:介入治疗术后残留肿瘤及良性强化区的最大增强斜率(MSI)差异有显著性意义;残留或复发肿瘤的时间-信号强度曲线为快速上升型;良性强化组织的时间-信号强度曲线为缓慢上升型;PWI对肝脏介入治疗后肿瘤残留、复发检测的敏感度为0.89,特异度为0.73。结论:PWI对肝脏肿瘤介入治疗术后的组织类型区别是一种非常敏感的功能成像技术,能够在肝癌介入治疗术后病变的早期发现肿瘤残留及复发。

Objective：To investigate the value of MR perfusion imaging in evaluating the curative effect of interventional treatment of liver cancer. Methods： Thirty-six patients underwent MR perfusion imaging after transcatheter arterial chemoembolization and radiofrequency ablation. The quantitative results were compared between carcinoma residue and benign tissue. And the diagnostic accuracy was judged. Results：There was a significant difference in mean MSI between tumor residue and the benign enhancement area. The time-signal intensity curve of residual tumor was observed to ascend rapidly to reach the peak,whereas that of the enhancement tissue ascended slowly to reach the peak. The sensitivity and specificity of PWI on detection of residual or recurrent tumor was 0.89 and 0. 73 respectively. Conclusion：PWI is a very sensitive imaging technique that can be used to distinguish liver tissue condition after interventional treatment of liver cancer. PWI contributed to early stage diagnosis and dynamic monitoring following interventional treatment of liver cancer.