慢性酒精中毒所致脑病的影像学表现

Radiologic study in chronic alcoholism-induced encephalopathy

目的:探讨慢性酒精中毒性脑病的临床及影像学改变。方法:回顾性分析36例慢性酒精中毒性脑病的临床和CT、MRI表现。结果:36例患者均有不同程度的精神及意识障碍,其中17例为急性起病,13例为亚急性起病,6例为慢性起病。36例均有不同程度脑皮质萎缩,8例小脑萎缩,8例表现为脑白质脱髓鞘,10例符合胼胝体变性,6例符合韦尼克脑病,4例符合桥脑中央髓鞘溶解症。结论:慢性酒精中毒性脑病有其特征性影像学表现,MRI对其诊断、治疗及预后评价具有重要价值。

Objective：To investigate the clinicoradiologic characteristics of chronic alcoholism-related encephalopathy. Methods： The clinical and neuroimaging findings in 36 patients diagnosed as chronic alcoholism-indueed encephalopathy were retrospectively analyzed. Five cases only had CT examinations and 21 cases only had MR imaging studies with both studies were performed in ten cases.Results： Variable degrees of psychic and conscious disorders presented in all patients with acute onset in seventeen cases, subacute onset in thirteen and chronic in six. Different degrees of braln coedcal atrophy demonstrated in all patients with eerebellar atrophy（8）, and white hintter demyelination（8）,Marchiafava-Bignami disease（10）, Wernicke eneephalopathy（6） and central pontine myelinolysis（4）. Conclusion： The MR imaging features of chronic alcoholism-indueed encephalopathy is characteristic and may be associated with the clinical spectrum and prognosis.