摘要
人巨细胞病毒(HCMV)在人群中普遍易感,免疫力正常者多为隐性感染,可终身携带病毒。感染后,病毒激活机体免疫系统,产生病毒清除作用。在机体清除HCMV的免疫应答中,与机体其他免疫相比,固有免疫中的免疫细胞和获得性免疫中的细胞免疫起着更为重要的作用,同时巨细胞病毒也通过一系列的逃逸反应来对抗上述免疫的清除作用。
Human cytomegalovirus is one of the most common viral opportunistic pathogen among patients. Most of infections are generally asymptomatic or self-healing. The immune system of host is activated after being infected in order to eliminate the pathogen. Immunocyte and cellular immunity play much more important roles during the reaction compared with other immunities. Meanwhile, human cytomegalovirus may take some escape reactions against the cell-mediated immunity.
出处
《国际流行病学传染病学杂志》
CAS
2008年第3期182-184,I0004,共4页
International Journal of Epidemiology and Infectious Disease
基金
国家973项目(2007CB513005)
国家自然科学基金(30471631)
浙江省卫生厅基金(2002ZX028,20058B42)
关键词
巨细胞病毒
细胞
免疫
逃逸反应
Cytomegalovirus
Cellular
Immunity
Escape reaction