1Lurton JM,Trejo T,Narayanan AS,et al.Pirfenidone inhibits the stimulatory effects of profibrotic cytokines on human lung fibroblasts in vitro[].American Journal of Respiratory and Critical Care Medicine.1996
2Raghu G,Johnson WC,Lockhart D,et al.Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone:results of a prospective,open-label PhaseⅡstudy[].American Journal of Respiratory and Critical Care Medicine.1999
3Simone NL,Soule BP,Gerber L,et al.Oral Pirfenidone in patients with chronic fibrosis resulting from radiotherapy:a pilot study[].Radiotherapy and Oncology.2007
4Azuma A,Nukiwa T,Tsuboi E,et al.Double-blind,placebo- controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis[].American Journal of Respiratory and Critical Care Medicine.2005
5Aono Y,Nishioka Y,Inayama M,et al.Imatinib as a novel antifibrotic agent in bleomycin-induced pulmonary fibrosis in mice[].The Journal of Experimental Medicine.2005
7Tzortzaki EG,Antoniou KM,Zervou MI,et al.Effects of antifibrotic agents on TGF-betal,CTGF and IFN-gamma expression in patients with idiopathic pulmonary fibrosis[].Respiratory Medicine.2007
9Nathan SD,Barnett SD,Moran B,et al.Interferon gamma-1b as therapy for idiopathic pulmonary fibrosis.An intrapatient analysis[].Respiration.2004
10Raghu G,Brown KK,Bradford WZ,et al.A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis[].The New England Journal of Medicine.2004
4Miachael C, Surrenti C, Milani S. Trans forming growth factors beta1 And beta2 are differentially expresse dinfibroticliv erdisease. Bone JointSurge, 1991, (73) : 1418.
5Toshikazu Nakamura, Katsuhiko Nawa and Akira Ichihara. Partial Purification and Characterization of Hepatocyte Growth Factor from Serum of Hepatectomized Rats. Biochemical and Biophysical Research Communications, 1984, ( 3 ) : 1450-1459.
6Toshikazu Nakamura, Tsutomu Nishizawa, Mitchio Hagiya et al. Molecular cloning and expression of human hepatocyte growth factor. Letters To Nature, 1989 (23) :440-442.
7Noji S, Tashiro K, Koyama E, et al. Expression of hepatocyte growth factor gene in endothelial and kupffer cells of damaged rat livers, as revealed by in situ hybridization. Biochem Biophys Res Commun, 1990,173 ( 1 ) :42-47.
8Ramadori G, Neubauer K, Odenthal M, et al. The gene of hepatocyte growth factor is expressed in fat-storing cells of rat liver and is down regulated during cell growth and by transforing growth factor beta. Biochem Biophys Res Commun, 1992,183(2) :739-742.
9Nishino T, Kaise N, Sindo Y, et al. Promyelocytic leukemia cell line, HL-60, produces human hepatocyte growth factor. Biochem Biophys Res Commun, 1991 ; 181 ( 1 ) :323-330.
10Yoshinaga Y, Fujita S, Gotoh M, et al. Human lung cancer cell line producing hepatocyte growth factor/scatter factor. Jpn J Cancer Res, 1992,83 (12) : 1257-1261.