期刊文献+

烟酸对透析患者高密度脂蛋白水平及高磷血症的改善 被引量:4

下载PDF
导出
摘要 近四十多年来烟酸及其衍生物作为一大类重要的调节脂代谢的药物广泛用于临床。与其他调节血脂的药物相比,它最大的特点是不仅可以降低甘油三酯、极低密度脂蛋白胆固醇、低密度脂蛋白胆固醇及脂蛋白a的水平,而且能有效增高高密度脂蛋白胆固醇(HDL-C)水平。烟酸可以提高透析患音血HDL-C水平,更适合透析合并低HDL-C血症患者,同时研究发现,对血液透析合并高磷血症的患者烟酸及其衍生物可以有效地降低血磷。且安全有效、价格低廉,在慢性肾脏病及透析患者中的应用前景广泛。
作者 王松 汪涛
出处 《世界临床药物》 CAS 2008年第2期74-78,共5页 World Clinical Drug
  • 相关文献

参考文献1

  • 1Krishnaswamy Sampathkumar,Manickam Selvam,Yesudas Santhakumari Sooraj,Sankaran Gowthaman,Rajappan Nair Prabha Ajeshkumar. Extended Release Nicotinic Acid – A Novel Oral Agent for Phosphate Control[J] 2006,International Urology and Nephrology(1):171~174

同被引文献59

  • 1Frazlo JM, Adrago T. Non-calcium-containing phosphate binders: comparing efficacy, safety, and other clinical effects. Nephron Clin Pract,2012,120(2) : 108-119.
  • 2Checherit IA, Smarandache D, David C,et al. Vascular calcifications in chronic kidney disease---clinical management. Rom J Morphol Embryol,2012,53( 1 ) :7-13.
  • 3Betas JS. Niacin and related compounds for treating hyperphosphatemia in dialysis patients.Semin Dial, 2008, :21 (3) :203-205.
  • 4Shahbazian H, Zafar Mohtashami A, Ghorbani A,et al. Oral nicotinamide reduces serum phosphorus, increases HDL, and induces thrombocytopenia in hemodialysis patients: a double-blind randomized clinical trial.Nefrologia, 2011,31 ( 1 ) : 58-65.
  • 5Vasantha J, Soundararajan P, Vanitharani N, et al. Safety and efficacy of nicotinamide in the management of hyperphosphatemia in patients on hemedialysis. Indian J Nephrol, 2011,21 (4) : 245-249.:913-918.
  • 6Sampathkumar K.Niacin and analogs for phosphate control in dialysis--trerspective from a developing country. Int Urol Nephrol, 2009,41(4).
  • 7Kestenbaum B,Sampson J N,Rudser K D,et al.Serum phosphate levels and mortality risk among people with chronic kidney disease[J].J Am Soc Nephrol,2005,16:520 528.
  • 8Hutchison A J.Improving phosphate-binder therapy as a way forward[J].Nephrol Dial Transplant,2004,19 Suppl 1:i19-i24.
  • 9Mitsopoulos E,Griveas I,Zanos S,et al.Increase in serum magnesium level in haemodialysis patients receiving sevelamcr hydrochloride[J].Int Urol Nephrol,2005,37:321-328.
  • 10Cheng S C,Young D O,Huang Y,et al.A randomized,double-blind,placebo-controlled trial of niacinamide for reduction of phosphorus in hemodialysis patients[J].Clin J Am Soc Nephrol,2008,3:l131-1138.

引证文献4

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部