“白黄液”预防脑出血并发应激性溃疡出血的疗效观察

Observation on therapeutic efficacy of “bai huang” juice on preventing cerebral haemorrhage complicated stressulcer bleeding

目的：观察中药“白黄液”预防脑出血并发应激性溃疡出血的疗效。方法：脑出血患者１１０例，随机分为观察组６１例及对照组４９例，观察组在对照组常规治疗的基础上加口服或胃管注入“白黄液”。结果：观察组并发应激性溃疡出血５例（８．２％），死亡４例（６．６％）；对照组并发应激性溃疡出血及病死分别为２１例（４２．９％）和１１例（２２．４％）。２组应激性溃疡发生率和病死率比较均有显著性差异（Ｐ均＜０．０１）。结论：“白黄液”能有效地预防应激性溃疡出血的发生，降低病死率，为预防脑出血并发应激性溃疡出血和降低病死率的有效药物，值得推广使用。

Objective:To observe the effect of “bai huang” juice (BHJ,) on preventing cerebral haemorrhage complicated stressulcer bleeding.Methods:One hundred and ten cases of cerebral haemorrhage were divided randomly into observation group (61 cases) and control group(49 cases).The observation group was treated with BHJ on the basis of conventional therapy;control group was treated with conventional therapy alone.Results:Five cases with cerebral haemorrhage were complicated stressulcer bleeding (82%) and 4 cases were died (66%) in observation group,while 21 cases were complicated stressulcer bleeding (429%) and 11 cases were died (224%) in control group.There have obvious difference in morbidity of stressulcer and mortality between 2 groups (all P<001).Conclusions:BHJ can prevent effectively the stressulcer bleeding and decrease mortality.So it is an idea drug for preventing stressulcer bleeding induced by cerebral haemorrhage and decreasing mortality.