3Guan Y, Breyer MD. Peroxisome proliferator - activated receptors (PPARs) :Novel therapeutic targets in renal disease. Kidney Int ,2001,60 : 14-30.
4Nukamura T, Ushiyama C, Suzuki S, et al. Effect of troglitazone onurinary albumin excretion and serum type Ⅳ collagen concentrations intype 2 diabetic patients with microalbuminuria or macroalbuminuria. Diabet Med, 2001,18 : 308- 313.
5Hsueh WA, Bruemmer D. Peroxisome proliferator-activated receptor gamma: implications for cardiovascular disease. Hypertension ,2004,43:297-305.
3Lu HE,Jian CH,Chen SF,et al.Hypoglycaemic effects of fermented mycelium of Paecilomyces farinosus(G30801)on high-fat fed rats with streptozotocin-induced diabetes[J].Indian J Med Res,2010,131:696-701.
4Madkor HR,Mansour SW,Ramadan G.Modulatory effects of garlic,ginger,turmeric and their mixture on hyperglycaemia,dyslipidaemia and oxidative stress in streptozotocin-nicotinamide diabetic rats[J].Br J Nutr,2011,105(8):1210-1217.
5Arya A,Yadav HN,Sharma PL.Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats[J].Mol Cell Biochem,2011,354(1-2):57-66.
7Kim SH,Jang YW,Hwang P,et al.The reno-protective effect of a phosphoinositide3-kinase inhibitor wortmannin on streptozotocin-in-duced proteinuric renal disease rats[J].Exp Mol Med,2012,44(1):45-51.
8Nishiyama A,Kobori H,Konishi Y,et al.Mineralocorticoid re ceptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type2diabetic rats[J].J Pharmacol Exp Ther,2010,332(3):1072-1080.
9Pilmore HL.Review:metformin:potential benefits and use in chronic kidney disease[J].Nephrology(Carlton),2010,15(4):412-418.
10Alhaider AA,Korashy HM,Sayed-Ahmed MM,et al.Metformin at-tenuates streptozotocin-induced diabetic nephropathy in rats through modulation of oxidative stress genes expression[J].Chem Biol In-teract,2011,192(3):233-242.
