衡阳市2005-2006年麻疹IgM抗体检测结果分析

Detection Results of Measles IgM Antibody in Hengyang from 2005 Through 2006

目的探讨麻疹IgM抗体检测对判断麻疹疑似病例的意义。方法采用酶联免疫吸附试验(ELISA),对麻疹疑似病例的血清标本进行麻疹特异性抗体检测。结果2005-2006年两年间收集787例麻疹疑似病例,检测IgM抗体阳性率为51.3%,其中小于1岁年龄组为11.6%;1～4岁年龄组为52.2%;5～15岁年龄组为32.7%;大于15岁年龄组为3.5%。阳性患者的构成比呈低龄化趋势,抗体阳性者中33.4%有免疫史。不同采血时间,抗体的阳性率差异有统计学意义。结论麻疹的计划免疫工作应加强基础免疫和复种工作,提高接种质量,同时重视病例的流行病学、免疫学监测。

Objective To explore the significance of detecting measles IgM antibody in diagnosis of suspected measles cases. Method Serum specimens of suspected measles cases were tested for measles IgM antibody by ELISA. Results A total of 787 suspected measles cases were collected to detect measles IgM antibody during the period of 2005- 2006, and the positive rate was 51.3%, which was composed by 11.6% in the 〈 1- year group, 52.2% in the 1--4 years group, 32.7% in the 5--15 years group, and 3.5% in the 〉15 years group. 33.4% of the positive cases had immunity history of measles vaccination, and the age of the positive case tended to youngster. IgM antibody positive rates were different according to sample collecting time. Conclusions Basic immunization and immunological surveillance of measles should be implemented to control and eliminate measles.