思连康预防小儿肺炎继发腹泻的临床观察

Observational Study of Siliankang in Preventing Diarrhea Complication in Pediatric Pneumonia Cases

目的探讨应用微生态制剂思连康(口服双歧杆菌、乳杆菌、肠球菌、蜡样芽孢杆菌四联活菌片)预防小儿肺炎继发腹泻的疗效。方法我院儿科住院治疗的小儿肺炎366例,预防组190例,对照组176例。对照组给予抗生素等对症支持治疗,预防组在使用抗生素治疗的同时加用思连康,然后对两组继发腹泻的发病率、疗效、止泻时间及腹泻总病程进行统计分析。结果预防组继发腹泻31例,发病率为16.32%,对照组继发腹泻67例,发病率38.07%(χ2=22.0493,P<0.01)。预防组治疗小儿肺炎继发腹泻的止泻时间、腹泻总病程亦明显短于对照组(P<0.05)。结论思连康能降低小儿肺炎继发腹泻的发病率,预防性应用具有积极的临床意义。

Objective To determine the efficacy of Siliankang（Oombined Bifidobacterium, Lactobacillus. Enterococcus and Bacillus cereus Tablets（Live）, Oral）in preventing diarrhea complication in pneumonia children. Methods Totally 366 inpatients with pediatric pneumonia were assigned into two groups, 190 cases in experimental group were treated with Siliankang in addition to antibiotics and 176 cases in the control group were treated with antibiotics alone. The subsequent diarrhea occurrence rate and efficacy, including the duration of diarrhea control and hospital stay were comparedbetween the two groups. Results Altogether 31 cases of the experimental group occurred diarrhea, with the incidence of 16.32 % ; 67 cases of the control group occurred diarrhea, with the incidence of 38.07 %. There showed statistical significant differences between the two groups （X2 = 22. 0493, P〈 0.01）. The diarrhea control and hospital stay showed significant difference too （ P 〈 0.05）. Conclusions Siliankang can efficiently prevent diarrhea complication in pediatric pneumonia.